Trazodone hydrochloride overdose. Trazodone is an antidepressant medicine. Sometimes, it is used as a sleep aid and to treat agitation in people with dementia. Trazodone overdose occurs when someone takes more than the normal or recommended amount of this medicine, either by accident or on purpose. This article is for information only. Trazodone is a triazolopyridine derivative that belongs to the class of serotonin receptor antagonists and reuptake inhibitors (SARIs). The drug is approved and marketed in several countries worldwide for the treatment of major depressive disorder (MDD) in adult patients. In clinical studies, trazodone has demonstrated comparable antidepressant Aim: To provide a review of the clinically relevant evidence pertaining to the use of trazodone in major depressive disorder. Methods: Medline and Cochrane Library searches were searched using the keywords 'trazodone' AND 'depression', to identify the most relevant literature pertinent to the pharmacological properties of trazodone and its use in clinical practice. Strengths: 25 mg, 50 mg, 100 mg; Form: Oral solution; Strengths: 20 mg/mL; Dosage for major depressive disorder. Adult dosage (ages 18–64 years) The typical starting dose is 50 mg per day. Dosage for Sleep. Trazodone tablets come in multiple doses: 50mg; 100mg; 150mg; 300mg; When used as a sleep aid, start off with 25 to 50mg and increase the dose if necessary up to 100mg. Studies have also shown that trazodone has utility even in lower doses. Overview. Trazodone is most frequently used as an “off-label” agent in the treatment of insomnia.45 Whereas it is generally used at a dosage of 200 to 600 mg in the treatment of depression, the dosage used to treat insomnia typically ranges from 25 to 150 mg. With a T max of 1 to 2 hours and a T 1/2 of 7 to 15 hours, trazodone has the Trazodone is widely prescribed in the U.S. due to its low risk of dependability (not classified as a controlled substance by the FDA) and the fact that you can purchase a month’s supply for as low as $4. Figures by Statista show that the annual prescriptions of the drug in the U.S. stand at over 20 million. trazodone 50 mg tablet Trazodone (TRZ) is a compound with a multi-modal mechanism of action, being a serotonin-2 antagonist/reuptake inhibitor approved in several countries for the treatment of depression with or without anxiety, with a daily dosage range of 150–600 mg . OzUL.

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